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1

Identification of small-molecule inhibitors of the Aβ–ABAD interaction

Yuli Xie, Shixian Deng, Zhenzhang Chen, Shidu Yan, Donald W. Landry

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 159 KB

english, 2006

2

A Method for Removing the Effect of the Camera Radiance on the Infrared Image

Shidu Dong, Xiaofan Yang, Wu Yang, He Yan, Yue Wang

Journal:

Journal of Infrared, Millimeter and Terahertz Waves

Year:

2008

Language:

english

File:

PDF, 219 KB

english, 2008

3

Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system

Yan, Shirley Shidu, Wu, Zhi-Ying, Zhang, Hui Ping, Furtado, Glaucia, Chen, Xi, Yan, Shi Fang, Schmidt, Ann Marie, Brown, Chris, Stern, Alan, Lafaille, Juan

Journal:

Nature Medicine

Year:

2003

Language:

english

File:

PDF, 622 KB

english, 2003

4

Surface Plasmon Resonance and Nuclear Magnetic Resonance Studies of ABAD−Aβ Interaction†

Liu, Yangzhong, Sorci, Mirco, Belfort, Georges, Yan, Yilin, Lustbader, Joyce W., Yan, Shirley ShiDu, Wang, Chunyu

Journal:

Year:

2007

Language:

english

File:

PDF, 253 KB

english, 2007

5

Mitochondrial permeability transition pore in Alzheimer's disease: Cyclophilin D and amyloid beta

Heng Du, Shirley ShiDu Yan

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2010

Language:

english

File:

PDF, 449 KB

english, 2010

6

Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model

Fang Fang, Xiaochun Chen, Tianwen Huang, Lih-Fen Lue, John S. Luddy, Shirley ShiDu Yan

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2012

Language:

english

File:

PDF, 642 KB

english, 2012

7

Mitochondrial medicine for neurodegenerative diseases

Heng Du, Shirley ShiDu Yan

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2010

Language:

english

File:

PDF, 570 KB

english, 2010

8

Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model

Heng Du, Lan Guo, Wensheng Zhang, Monika Rydzewska, Shidu Yan

Journal:

Neurobiology of Aging

Year:

2011

Language:

english

File:

PDF, 1.12 MB

english, 2011

9

Genetic deficiency of RAGE protects against Aβ accumulation in an Alzheimer mouse model via modulating beta and gamma secretase activity

Fang Fang, Shiqiang Yan, Hung L. Nguyen, Shirley Shidu Yan

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 64 KB

english, 2010

10

Synaptic Mitochondrial Pathology in Alzheimer's Disease

Du, Heng, Guo, Lan, Yan, Shirley ShiDu

Journal:

Antioxidants & Redox Signaling

Year:

2012

Language:

english

File:

PDF, 427 KB

english, 2012

11

Acetylcholinesterase Inhibitors: Structure Based Design, Synthesis, Pharmacophore Modeling, and Virtual Screening

Valasani, Koteswara Rao, Chaney, Michael O., Day, Victor W., ShiDu Yan, Shirley

Journal:

Journal of Chemical Information and Modeling

Year:

2013

Language:

english

File:

PDF, 5.78 MB

english, 2013

12

Mitochondrial permeability transition pore is a potential drug target for neurodegeneration

Rao, Valasani Koteswara, Carlson, Emily A., Yan, Shirley Shidu

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2014

Language:

english

File:

PDF, 664 KB

english, 2014

13

Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell

Gan, Xueqi, Huang, Shengbin, Wu, Long, Wang, Yongfu, Hu, Gang, Li, Guangyue, Zhang, Hongju, Yu, Haiyang, Swerdlow, Russell Howard, Chen, John Xi, Yan, Shirley ShiDu

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2014

Language:

english

File:

PDF, 1.68 MB

english, 2014

14

Identification of human presequence protease (hPreP) agonists for the treatment of Alzheimer's disease

Vangavaragu, Jhansi Rani, Valasani, Koteswara Rao, Gan, Xueqi, Yan, Shirley ShiDu

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.41 MB

english, 2014

15

Hypertension triggers vascular-related Alzheimer's by activation of RAGE

Carnevale, Daniela, Mascio, Giada, D'Andrea, Ivana, Yan, Shidu, Lembo, Giuseppe

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 183 KB

english, 2011

16

Ischemia as a trigger for RAGE-dependent synaptic dysfunction in an amyloid-enriched environment

Origlia, Nicola, Criscuolo, Chiara, Arancio, Ottavio, ShiDu Yan, Shirley, Domenici, Luciano

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 54 KB

english, 2012

17

The potential role of damage-associated molecular patterns derived from mitochondria in osteocyte apoptosis and bone remodeling

Gan, Xueqi, Huang, Shengbin, Liu, Yang, Yan, Shirley ShiDu, Yu, Haiyang

Journal:

Year:

2014

Language:

english

File:

PDF, 136 KB

english, 2014

18

P3-379

Wang, Chunyu, Yan, Yilin, Liu, Yangzhong, Yan, Shirley ShiDu, Xu, Hong Wei

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 55 KB

english, 2006

19

P4-328

Yao, Jun, Xu, Hong Wei, Luddy, John, Chen, Xi, Arancio, Ottavio, Yan, ShiDu

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 58 KB

english, 2006

20

Cyclophilin D deficiency rescues Aβ-impaired PKA/CREB signaling and alleviates synaptic degeneration

Du, Heng, Guo, Lan, Wu, Xiaoping, Sosunov, Alexander A., McKhann, Guy M., Chen, John Xi, Yan, Shirley ShiDu

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2014

Language:

english

File:

PDF, 1.15 MB

english, 2014

21

Structure Based Design, Synthesis, Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies for Identification of Novel Cyclophilin D Inhibitors

Valasani, Koteswara Rao, Vangavaragu, Jhansi Rani, Day, Victor W., Yan, Shirley ShiDu

Journal:

Journal of Chemical Information and Modeling

Year:

2014

Language:

english

File:

PDF, 1.51 MB

english, 2014

22

From a cell's viewpoint: targeting mitochondria in Alzheimer's disease

Carlson, Emily Ann, Rao, Valasani Koteswara, Yan, Shirley ShiDu

Journal:

Drug Discovery Today: Therapeutic Strategies

Year:

2013

Language:

english

File:

PDF, 1.43 MB

english, 2013

23

Multi-faced neuroprotective effects of geniposide depending on the RAGE-mediated signaling in an Alzheimer mouse model

Lv, Cui, Wang, Lei, Liu, Xiaoli, Yan, Shijun, Yan, Shirley ShiDu, Wang, Yongyan, Zhang, Wensheng

Journal:

Neuropharmacology

Year:

2015

Language:

english

File:

PDF, 2.22 MB

english, 2015

24

[IEEE Second Workshop on Digital Media and its Application in Museum & Heritages (DMAMH 2007) - ngqing, China (2007.12.10-2007.12.12)] Second Workshop on Digital Media and its Application in Museum & Heritages (DMAMH 2007) - An Improved Two-Point-Correction Method to Remove the Effect of the Radiance from Camera Interior on Infrared Image

Dong, Shidu, Yan, He, Jiang, Qun, He, Bo, Wang, Huaqiu

Year:

2007

Language:

english

File:

PDF, 389 KB

english, 2007

25

MAPK, β-amyloid and synaptic dysfunction: the role of RAGE

Origlia, Nicola, Arancio, Ottavio, Domenici, Luciano, Yan, Shirley ShiDu

Journal:

Expert Review of Neurotherapeutics

Year:

2009

Language:

english

File:

PDF, 1.10 MB

english, 2009

26

Drp1-Mediated Mitochondrial Abnormalities Link to Synaptic Injury in Diabetes Model

Huang, Shengbin, Wang, Yongfu, Gan, Xueqi, Fang, Du, Zhong, Changjia, Wu, Long, Hu, Gang, Sosunov, Alexander A., McKhann, Guy M., Yu, Haiyang, Yan, Shirley ShiDu

Journal:

Year:

2015

Language:

english

File:

PDF, 3.43 MB

english, 2015

27

Oxidative stress-mediated activation of extracellular signal-regulated kinase contributes to mild cognitive impairment-related mitochondrial dysfunction

Gan, Xueqi, Wu, Long, Huang, Shengbin, Zhong, Changjia, Shi, Honglian, Li, Guangyue, Yu, Haiyang, Howard Swerdlow, Russell, Xi Chen, John, Yan, Shirley ShiDu

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 2.18 MB

english, 2014

28

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

Du, H., Guo, L., Yan, S., Sosunov, A. A., McKhann, G. M., ShiDu Yan, S.

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 884 KB

english, 2010

29

Overexpression of 17β-hydroxysteroid dehydrogenase type 10 increases pheochromocytoma cell growth and resistance to cell death

Carlson, Emily A, Marquez, Rebecca T, Du, Fang, Wang, Yongfu, Xu, Liang, Yan, Shirley ShiDu

Journal:

Year:

2015

Language:

english

File:

PDF, 3.31 MB

english, 2015

30

High-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 molecules

Valasani, Koteswara Rao, Carlson, Emily A., Battaile, Kevin P., Bisson, Andrea, Wang, Chunyu, Lovell, Scott, Yan, Shirley ShiDu

Journal:

Acta Crystallographica Section F Structural Biology Communications

Year:

2014

Language:

english

File:

PDF, 737 KB

english, 2014

31

Ginsenoside Rg1 Attenuates Oligomeric Aβ1-42-Induced Mitochondrial Dysfunction

Huang, Tianwen, Fang, Fang, Chen, Limin, Zhu, Yuangui, Zhang, Jing, Chen, Xiaochun, Shidu Yan, Shirley

Journal:

Current Alzheimer Research

Year:

2012

Language:

english

File:

PDF, 530 KB

english, 2012

32

NR2B-dependent Cyclophilin D translocation suppresses the recovery of synaptic transmission after oxygen-glucose deprivation

Zhang, Zhihua, Wang, Yongfu, Yan, Shijun, Du, Fang, Yan, Shirley Shidu

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2015

Language:

english

File:

PDF, 660 KB

english, 2015

33

Hypoxia Inducible Factor-1 as a Target for Neurodegenerative Diseases

Zhang, Z., Yan, J., Chang, Y., ShiDu Yan, S., Shi, H.

Journal:

Current Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 321 KB

english, 2011

34

Blockade of Drp1 rescues oxidative stress-induced osteoblast dysfunction

Gan, Xueqi, Huang, Shengbin, Yu, Qing, Yu, Haiyang, Yan, Shirley ShiDu

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 1.31 MB

english, 2015

35

Corrigendum to “Identification of human presequence protease (hPreP) agonists for the treatment of Alzheimer's disease” [Eur. J. Med. Chem. 76 (2014) 506–516]

Vangavaragu, Jhansi Rani, Valasani, Koteswara Rao, Gan, Xueqi, ShiDu Yan, Shirley

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 134 KB

english, 2015

36

Identification of a Small Molecule Cyclophilin D Inhibitor for Rescuing Aβ-Mediated Mitochondrial Dysfunction

Valasani, Koteswara Rao, Sun, Qinru, Fang, Du, Zhang, Zhihua, Yu, Qing, Guo, Yaopeng, Li, Jianping, Roy, Anuradha, ShiDu Yan, Shirley

Journal:

ACS Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 936 KB

english, 2016

37

Early deficits in synaptic mitochondria in an Alzheimer’s disease mouse model

Heng Du, Lan Guo, Shiqiang Yan, Alexander A. Sosunov, Guy M. McKhann, Shirley ShiDu Yan and Pedro M. Cuatrecasas

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.47 MB

english, 2010

38

[IEEE Second Workshop on Digital Media and its Application in Museum & Heritage (DMAMH 2007) - Chongqing, P.R., China (2007.12.10-2007.12.12)] Second Workshop on Digital Media and its Application in Museum & Heritage (DMAMH 2007) - An Improved Two-Point-Correction Method to Remove the Effect of the Radiance from Camera Interior on Infrared Image

Dong, Shidu, Yan, He, Jiang, Qun, He, Bo, Wang, Huaqiu

Year:

2007

Language:

english

File:

PDF, 389 KB

english, 2007

39

F 1 F 0 ATP Synthase-Cyclophilin D Interaction Contributes to Diabetes-Induced Synaptic Dysfunction and Cognitive Decline

Yan, Shijun, Du, Fang, Wu, Long, Zhang, Zhihua, Zhong, Changjia, Yu, Qing, Wang, Yongfu, Lue, Lih-Fen, Walker, Douglas G., Douglas, Justin T., Yan, Shirley Shidu

Journal:

Year:

2016

Language:

english

File:

PDF, 2.62 MB

english, 2016

40

Development and Dynamic Regulation of Mitochondrial Network in Human Midbrain Dopaminergic Neurons Differentiated from iPSCs

Fang, Du, Qing, Yu, Yan, Shijun, Chen, Doris, Yan, Shirley ShiDu

Journal:

Stem Cell Reports

Year:

2016

Language:

english

File:

PDF, 4.20 MB

english, 2016

41

Mfn2 is Required for Mitochondrial Development and Synapse Formation in Human Induced Pluripotent Stem Cells/hiPSC Derived Cortical Neurons

Fang, Du, Yan, Shijun, Yu, Qing, Chen, Doris, Yan, Shirley ShiDu

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.94 MB

english, 2016

42

Mitochondrial Dysfunction, Endoplasmic Reticulum Stress, and Apoptosis in Alzheimer’s Disease

Takuma, Kazuhiro, Yan, Shirley ShiDu, Stern, David M., Yamada, Kiyofumi

Journal:

Journal of Pharmacological Sciences

Year:

2005

Language:

english

File:

PDF, 202 KB

english, 2005

43

CROSSTALK OF MITOCHONDRIA TO SYNAPTIC DYSFUNCTION IN ALZHEIMER DISEASE

ShiDu Yan, Shirley

Journal:

Alzheimer's & Dementia

Year:

2016

Language:

english

File:

PDF, 42 KB

english, 2016

44

Entorhinal Cortex dysfunction can be rescued by inhibition of microglial RAGE in an Alzheimer’s disease mouse model

Criscuolo, Chiara, Fontebasso, Veronica, Middei, Silvia, Stazi, Martina, Ammassari-Teule, Martine, Yan, Shirley ShiDu, Origlia, Nicola

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.74 MB

english, 2017

45

Increased Electron Paramagnetic Resonance Signal Correlates with Mitochondrial Dysfunction and Oxidative Stress in an Alzheimer’s disease Mouse Brain

Fang, Du, Zhang, Zhihua, Li, Hang, Yu, Qing, Douglas, Justin T., Bratasz, Anna, Kuppusamy, Periannan, Yan, Shirley ShiDu, Reddy, Hemachandra

Journal:

Journal of Alzheimer's Disease

Year:

2016

Language:

english

File:

PDF, 348 KB

english, 2016

46

Mitochondrial Dysfunction Triggers Synaptic Deficits via Activation of p38 MAP Kinase Signaling in Differentiated Alzheimer’s Disease Trans-Mitochondrial Cybrid Cells

Yu, Qing, Du, Fang, Douglas, Justin T., Yu, Haiyang, Yan, Shirley ShiDu, Yan, Shi Fang, Reddy, Hemachandra

Journal:

Journal of Alzheimer's Disease

Year:

2017

Language:

english

File:

PDF, 824 KB

english, 2017

47

Antioxidants Rescue Mitochondrial Transport in Differentiated Alzheimer’s Disease Trans-Mitochondrial Cybrid Cells

Yu, Qing, Fang, Du, Swerdlow, Russell Howard, Yu, Haiyang, Chen, John Xi, Yan, Shirley ShiDu, Reddy, P. Hemachandra

Journal:

Journal of Alzheimer's Disease

Year:

2016

Language:

english

File:

PDF, 594 KB

english, 2016

48

PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer’s disease

Du, Fang, Yu, Qing, Yan, Shijun, Hu, Gang, Lue, Lih-Fen, Walker, Douglas G, Wu, Long, Yan, Shi Fang, Tieu, Kim, Yan, Shirley ShiDu

Journal:

Year:

2017

Language:

english

File:

PDF, 2.57 MB

english, 2017

49

ALTERATIONS IN MITOCHONDRIAL NETWORK CONTRIBUTE TO SYNAPTIC DYSFUNCTION IN DIABETIC ALZHEIMER'S DISEASE MOUSE MODELS

Yu, Qing, Du, Fang, Hu, Gang, Yan, Shi Fang, ShiDu Yan, Shirley

Journal:

Alzheimer's & Dementia

Year:

2017

Language:

english

File:

PDF, 376 KB

english, 2017

50

RAGE mediates Aβ accumulation in a mouse model of Alzheimer’s disease via modulation of β- and γ-secretase activity

Fang, Fang, Yu, Qing, Arancio, Ottavio, Chen, Doris, Gore, Smruti S, Yan, Shi Fang, Yan, Shirley ShiDu

Journal:

Human Molecular Genetics

Year:

2018

Language:

english

File:

PDF, 10.12 MB

english, 2018

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